{"product_id":"glp-1-based-therapies-for-diabetes-obesity-and-beyond-1570659","title":"GLP-1-based therapies for diabetes, obesity and beyond","description":"\u003cp\u003eCoverage of GLP-1 weight-loss drugs is growing among the largest employers (5000+ workers), now at 43%\u003c\/p\u003e\n\u003cp\u003eBut the drugs are deemed generally safe by the FDA, and parents whose kids are taking them, and the doctors prescribing them, say the benefit of preventing or slowing the progression of obesity-related chronic conditions, such as type 2 diabetes and heart disease that worsen with age, outweighs these risks\u003c\/p\u003e\n\u003cp\u003eMalhotra has submitted a grant proposal to the National Institutes of Health to explore this issue\u003c\/p\u003e\n\u003cp\u003eSome patients find 200 to 400 mg at bedtime helps with both bowel regularity and sleep\u003c\/p\u003e\n\u003cp\u003e19 This research culminated in the development of dapagliflozin, canagliflozin, and empagliflozin, which were approved by the FDA between 2013 and 2014 for the treatment of T2D\u003c\/p\u003e\n\u003cp\u003eSemaglutide and liraglutide have been used for years with reassuring safety profiles\u003c\/p\u003e\n\u003cp\u003eGLP-1s Offer New Hope When Treatment Options Are Limited A growing share of providers are prescribing GLP‑1 therapies to manage multiple conditions, a trend particularly evident in comorbidities where few therapeutic options exist\u003c\/p\u003e\n\u003cp\u003eProtein requirements become critical Both menopause and GLP-1-induced weight loss put muscle mass at risk\u003c\/p\u003e\n\u003cp\u003eResearch shows that fatty liver disease is associated with a 64% increased risk of heart attack or stroke\u003c\/p\u003e\n\u003cp\u003ePatients may find themselves ruminating about health concerns, weight loss progress, or other life stressors\u003c\/p\u003e\n\u003cp\u003eHowever, it also has a positive effect on obesity\u003c\/p\u003e\n\u003cp\u003eUnderstanding Your $50 Copay Does it count toward my Part D deductible\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/media.springernature.com\/lw1200\/springer-static\/image\/art%3A10.1038%2Fs41573-025-01183-8\/MediaObjects\/41573_2025_1183_Fig4_HTML.png\" alt=\"GLP-1-based therapies for diabetes, obesity and beyond\"\u003e\u003c\/p\u003e","brand":"Other","offers":[{"title":"One size - default in the photo","offer_id":57096954380614,"sku":"cJO6UrTH-1","price":59.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9102\/0102\/files\/41573_2025_1183_Fig4_HTML.png?v=1786256869","url":"https:\/\/luckpolly.com\/products\/glp-1-based-therapies-for-diabetes-obesity-and-beyond-1570659","provider":"luck Polly","version":"1.0","type":"link"}